Википедија

Предлошка:Инфокутија Лек

(Пренасочено од Предлошка:Drugbox)
Инфокутија Лек
Икона за документација Документација за предлошка[преглед] [уреди] [историја] [превчитај]
Оваа предлошка содржи сложени примероци на предложна синтакса.
Ве молиме не ја менувајте синтаксата доколку не сте сосем запознаени со нејзиниот распоред и расчленувачките функции и сте подготвени да ги поправите или вратите сите пореметувања ако се појават неочекувани резултати.
Сите испробувања со измени врешете ги било во предложниот песочник или во вашиот кориснички простор пред да менувате било што тука.

Предлошка:Инфокутија Лек создава единствен изглед на сите статии за лекови и нуди дополнителни информации за лекот. При користење во статии, препорачуваме да го копирате кодот од соодветната статија за лекот на англиската Википедија, кој правилно ќе се прикаже во статијата овде.


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Кратенка:
{{Drugbox}}

Template:Infobox drug provides a consistent layout for drug articles and an interface to other sources that provide information about the drug. It can be used for single drugs, combination products (see #Combination products), monoclonal antibodies (see #Monoclonal antibody drugs) and vaccines (see #Vaccines). Don't worry about trying to fill in all the fields – even specifying just one or two can be useful.

Type of drug

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  • Set by |type=

Single chemical

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|type=<blank> Drugs that are a simple chemical compound. Short parameter list: 

{{Infobox drug
| drug_name         =
| type              =<!-- empty -->
| IUPAC_name        = 
| image             = 
| alt               = 
| caption           =
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment = 
| pregnancy_US      = <!-- A/B/C/D/X/N -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_DE = <!-- Anlage I, II, III -->
| legal_NZ = <!-- Class A, B, C -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_US = <!-- OTC/Rx-only/Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_status      = <!-- Free text -->
| routes_of_administration = 
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action =
| excretion         = 
<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
<!-- Chemical data -->
| chemical_formula  = 
| molecular_weight  = 
}}

Full single-drug template with extended fields: 

{{Infobox drug
| drug_name         =
| type              =<!-- empty -->
| IUPAC_name        = 
| image             = 
| width             = 
| alt               = 
| image2            = 
| width2            = 
| alt2              = 
| imageL            =
| widthL            =
| altL              = 
| imageR            = 
| widthR            = 
| altR              = 
| caption           = 
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        = <!-- EMA requires brand name -->
| licence_US        = <!-- FDA may use generic name -->
| DailyMedID        = <!-- preference to licence_US -->
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment =      
| pregnancy_US      = <!-- A / B            / C / D / X / N -->
| pregnancy_US_comment = 
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment = 
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment = 
| legal_DE = <!-- Anlage I, II, III or Unscheduled-->
| legal_DE_comment = 
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment = 
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment = 
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_US_comment = 
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_UN_comment = 
| legal_status      = <!--For countries not listed above-->
| dependency_liability = 
| addiction_liability = 
| routes_of_administration = 
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action =
| excretion         =
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChemCompound   = 
| PubChemSubstance  = 
| IUPHAR/BPS Guide to PHARMACOLOGY ligand ID     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| NIAID_ChemDB      =
| synonyms          = 
<!-- Chemical data -->
| chemical_formula  = 
| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=
| molecular_weight  = 
| SMILES            = 
| StdInChI          = 
| StdInChI_comment  = 
| StdInChIKey       = 
| density           = 
| melting_point     = 
| melting_high      = 
| melting_notes     = 
| boiling_point     = 
| boiling_notes     = 
| solubility        = 
| specific_rotation = 
| sec_combustion    = 
}}

OR alternatively: use Diberri's excellent Wikipedia template filling tool which will generate a populated template to copy & paste into an article if given a DrugBank ID number (which may be obtained from DrugBank search). Please select for Fill template vertically, but as Wikipedia is a general encyclopedia, most drugs do not warrant Show extended fields.

Combination of chemicals

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  • |type=combo

For drug-combinations, at least two components must be defined, with optional a 3rd and 4th component. For each component: 

| component1 =<!-- name, will be wikilinked -->
| class1     =<!-- class of agent, needs manual wikilinking -->

Example for Seretide: Предлошка:Infobox drug 

| drug_name  = Seretide
| type       = combo
| component1 = Fluticasone
| class1     = [[Glucocorticoid]]
| component2 = Salmeterol
| class2     = [[Beta2-adrenergic receptor agonist|Long-acting beta2 agonist]]

Generally combination articles will not need to display the molecular images of its constituents (the relevant specific articles would have the images). It disables all Chemical & Pharmacology parameters (which describe properties of single drug items). These redundant disabled parameters are best not included in the template calling, so use the following abridged forms of the template:

Shortened combination product form: 

{{Infobox drug
| drug_name         =
| type              = combo
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU          = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Full combination product template with extended fields and allowing for up to 4 items: 

{{Infobox drug
| drug_name         = 
| type              = combo
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->
| component3        = <!-- Drugname, automatically linked -->
| class3            = <!-- Group, manual link using [[..|..]] -->
| component4        = <!-- Drugname, automatically linked -->
| class4            = <!-- Group, manual link using [[..|..]] -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        = <!-- EMA requires brand name -->
| licence_US        = <!-- FDA may use generic name -->
| DailyMedID        = <!-- preference to licence_US -->
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| addiction_liability = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| synonyms          = 
}}

Monoclonal antibody drugs

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  • |type=mab

This form the box uses parameters: 

| type       = mab
| mab_type   =
| source     =
| target     =

For example Catumaxomab: Предлошка:Infobox drug 

| type       = mab
| mab_type   = 3funct
| source     = axo
| target     = [[EpCAM]], [[CD3 (immunology)|CD3]]

mab_type defines one of the following types of antibody or antibody fragment:

mab_type output
mab Whole antibody
Fab Fab fragment
F(ab')2 F(ab')2 fragment
Fab' Fab' fragment
scFv Single-chain variable fragment
di-scFv Di-single-chain variable fragment
sdAb Single domain antibody
3funct Trifunctional antibody
clFab Chemically linked Fab
BiTE Bi-specific T-cell engager

source is the species on which the protein sequence of the antibody is based:

source output
a Rat
e Hamster
i Primate
o Mouse
u Human
xi/a, xi/e, etc. Chimeric (rat/human) etc.
xi Chimeric [generic, use only if values above are not applicable]
zu/a, zu/e, etc. Humanized (from rat) etc.
zu Humanized [generic, use only if values above are not applicable]
xizu/a, xizu/e, etc. Chimeric/humanized hybrid (rat/human) etc.
xizu Chimeric/humanized hybrid [generic, use only if values above are not applicable]
axo Rat/mouse hybrid

target is the antigen at which the antibody is directed. This parameter takes free text as value, preferably including a wikilink such as |target=[[TNF-α]].

The drug name is followed by a "?" linked to Nomenclature of monoclonal antibodies, saving the need to explain how each monoclonal antibody has been named.

Shortened Monoclonal antibody form: 

{{Infobox drug
| type              = mab
| image             = 
| alt               = 
| mab_type          = <!-- mab, Fab, F(ab')2, Fab', scFv, di-scFv, 3funct, clFab, BiTE -->
| source            = <!-- a, e, i, o, u, xi/a, zu/a, xizu/a, axo, ... -->
| target            = <!-- antigen, not the code number of the monoclonal antibody! -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action=
| excretion         =
<!-- Identifiers -->
| CAS_number        = 
| ATC_prefix        = <!-- 'none' when not assigned -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Vaccines

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  • |type=vaccine

This allows the alternative parameters of the vaccine_type and target to be specified:

  • target can be any text. CAn be used to link to a specific article
  • vaccine_type must be from the defined list of options as described at Vaccine#Types, the infobox will provide standardised display and links as follows:
vaccine_type value Output
killed or inactivated Killed/Inactivated
attenuated Attenuated virus
live Live bacteria
toxoid Toxoid
protein or protein subunit Protein subunit
subunit Subunit
conjugate Conjugate vaccine
recombinant Recombinant Vector
DNA DNA vaccination

Where a vaccination product protects against more than one agent, please use the combination form of this infobox with type=combo (per #Combination products), and each classX=[[Vaccine]].

Shortened Vaccine form: 

{{Infobox drug
| drug_name         = 
| type              = vaccine
| image             = 
| alt               = 
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Full Vaccine template with extended fields: 

{{Infobox drug
| drug_name         =
| type              = vaccine
| image             = 
| alt               = 
| width             = 
| image2            = 
| alt2              = 
| width2            = 
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_EU        =  <!-- EMA requires brand name -->
| licence_US        =  <!-- FDA may use generic name -->
| DailyMedID        =  <!-- preference to licence_US -->
| pregnancy_AU      =  <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      =  <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| dependency_liability = 
| addiction_liability =
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| NIAID_ChemDB      =
}}

Parameters

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Names

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 | drug_name = 
 | IUPAC_name = 
 | tradename = 
 | synonyms =
See #Names and identifiers

Images

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You can use the image to provide an illustration. These fields are optional, but it is helpful to provide an image if you can find one. Of course most images on the internet are copyrighted.

You may specify the image name directly, else the template defaults to trying to use File:PAGENAME.png, where PAGENAME is the name of the drug article being written.

The alt parameter specifies the alt text for the image, used by visually impaired readers. See WP:ALT.

There is also an optional width parameter you can add for the image. If your picture is far too big, then add a new line and specify a custom width like this: 

 | image            = Aspirin.png
 | width            = 325

When no width parameter is specified, it defaults to a width of 220.

Occasionally a second image might be added to show the chemical structure in a different format. Use the optional image2 parameter for this. Hence the Paracetamol article uses: 

 | image            = Paracetamol-skeletal.png
 | image2           = Paracetamol-3D.png

An alt2 parameter specifies the alt text for the second image. image2 generally uses the same width settings as the first image, i.e. as defined by width otherwise a default value of 220. A specific width2 may though be applied. 

| image = 
| width = 
| alt = 
| image2 = 
| width2 = 
| alt2 = 
| caption = 
| imageL = 
| widthL = 
| altL = 
| imageR=
| widthR = 
| altR = 
| captionLR =

Clinical data

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| tradename =  
| Drugs.com =
| MedlinePlus =
  • tradename – comma separated list of tradenames
  • Drugs.com – link to Drugs.com monograph
  • MedlinePlus – MedlinePlus drug accession number

Pregnancy category

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Поврзано pregnancy category, documentation for extensive documentation

Pregnancy Categorisation has been previously declared using just the pregnancy_category parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively pregnancy_AU and pregnancy_US may be set to the fixed categories. For Australia values permitted are: A, B1, B2, B3, C, D or X (note if just set to 'B' then B? is shown). For US values permitted are: A, B, C, D or X.

Note the UK does not have official designated categorisations, but has both a variety of standard phrases with explanatory qualifications, plus many individual descriptions. The generic |pregnancy_category= acceptts any text, and may be used with such country-specific information (non AU or US).

For the new US labeling guidelines PLLR, parameter |PLLR= is added and will show any input text (not re-formatted). Hence 

  | pregnancy_AU = B1
  | pregnancy_AU_comment = any text
  | pregnancy_US = C
  | pregnancy_US_comment = any text
  | pregnancy_category = Used in pregnancy against [[Pregnancy-induced hypertension|PIH]]
  | PLLR = Some PLLR text

returns:

  • AU: B1 any text
  • US: C (Ризикот не е отфрлен) any text
  • US PLLR: Some PLLR text
  • Used in pregnancy against PIH
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Поврзано: {{Infobox drug/legal status}} for extensive documentation.

Legal status has been previously declared using just the legal_status parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively legal_AU, legal_EU legal_CA, legal_NZ, legal_UK, legal_UN, and legal_US may be set to the fixed options in the table hereafter. The template will ensure the categorisation is shown correctly capitalised, use Unicode Rx symbol and add a linked 2-letter country code as per WP:MOS. legal_status may still be used with the country-specific parameters as it is appended afterwards, allowing backwards compatibility for articles that only define this parameter, or for the future with free-text of other information.

Hence 

| legal_AU     = S2
| legal_AU_comment = any text
| legal_CA     = 
| legal_UK     = gsl
| legal_US     = Rx-only
| legal_EU     =
| legal_UN     =
| legal_NZ     = 
| legal_status = Not marketed in [[Asia]]

Returns:

  • AU: S2 (само во аптека) any text
  • NZ: temporary OTC in New Zealand
  • UK: General sales list (GSL, OTC)
  • US: само ℞
  • Not marketed in Asia

Note: if a drug is restricted everywhere to prescription-only, please set legal_status = Rx-only rather than similarly define for each and every country ('Rx-only' is specifically recognised by legal_status and shows as ℞ Prescription only)

Dependence liability

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Optional parameters Dependence liability and Addiction_liability allow opioids or benzodiazepines to be flagged with the risk of becoming dependent/addicted upon them, although in many cases this may be somewhat subjective. Drugs should be rated as Low, Medium, High or Extremely high: 

| dependency_liability = High
| addiction_liabiliy = High

Licensing information

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There are two major licensing authorities that make drug information easily accessible: The US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). NB: The word "licence" is the noun in British English, "license" is the verb.

The FDA "Label Information" and the EMA "Product Information", where available, are very detailed. There is material aimed at the professional and also plain-English consumer information. These are excellent reliable source for article information but also contains much that makes it a worthwhile "External link" since there is no way one can include all the info. Both sites work using of the brand name of the drug but the FDA site also allows searches with the generic name (active ingredient), which lists generic variants where they are licensed. 

| licence_EU = <!-- EMA requires brand name -->
| licence_US = <!-- FDA may use generic name -->

Lists of products and the parameter term to use may be easily searched for:

  • European Public Assessment Reports: SiteMap, authorised products A–Z: human, veterinary
    When items are composed of more than one word, licence_EU uses adjoined words (i.e. no spaces); e.g. infanrixpenta for Infanrix Penta.
  • Drugs@FDA Search by Drug Name or Active Ingredient
    Where items are composed of more than one word, licence_US requires an underscore '_' in place of any spaces; e.g. Acyclovir_Sodium.

More patient friendly than the FDA's pages is Daily Med which reproduces the same details. The DailyMedID parameter, where specified, is shown in preference to the licence_US direct FDA link. Daily Med entries may be located at Search By Drug Name, e.g. for Furosemide 

| DailyMedID = 3940

Pharmacokinetic data and routes of administration

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In general, these parameters are relevant ro a drug. Use wikilinks for values that the general reader might not understand (e. g. hepatic, CYP3A4, intraperitoneal). 

  | bioavailability   = 
  | protein_bound     = 
  | metabolism        = 
  | metabolites       =
  | onset             = 
  | elimination_half-life = 
  | duration_of_action= 
  | excretion         = 
  | routes_of_administration =

Names and identifiers

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Предлошка:Infobox drug/doc/names and identifiers

DrugBank

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The DrugBank primary accession number (consisting of a 2 letter prefix (DB) and a 5 number suffix). Secondary accession numbers with a 4 letter suffix (APRD, EXPT, BIOD, NUTR) should not normally be used.

PubChem

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When available, the PubChem compound identifier (CID) should be used because it is unique for each chemical compound: 

| PubChem        = 4091  <!-- Metformin -->

Make sure you choose the right CID: Often PubChem compound entries differ only very slightly, for example by an additional hydratation water or by a carbon atom with unspecified stereochemistry.

If no CID is available, which is usually the case when there is no structural information on PubChem, you may use one of the substance identifiers (SIDs): 

| PubChemSubstance    = 10099  <!-- Etanercept -->

The box won't display both CID and SID to avoid list cruft.

CAS Registry Number

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|CAS_number= Additional CAS codes may be included with optional |CAS_supplement= parameters in a comma-separated lists. CAS templates may be used to have these additional codes link to the relevant databases: 

| CAS_supplemental ={{CAS|427-51-0}} (acetate)

Adds the following linked codes:

For CAS - 427-51-0 (acetate)
  • Поврзано: Second identifiers and indexes

Verification, using parameters (like: CAS_number_Ref)

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Seven identfying parameters like |CAS_number=are tracked in a WP:Drugbox data validation process. A bot adds parameters like |verifiedrevid= and |CAS_number_Ref={{cascite|correct}}. Поврзано {{cascite}} documentation.

ATC, ATCvet

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Повеќе информации: Wikipedia:WikiProject Pharmacology/Style guide § Use ATC codes

Where the drug is not included in ATC coding system (as opposed to its value just not been entered into the template) then set ATC_prefix to 'none', and the article is automatically added to Category:Drugs not assigned an ATC code rather than Category:Drugboxes with an unspecified ATC code: 

| ATC_prefix        = none

Additional ATC may be included with the optional |ATC_supplemental= parameter as a comma-separated list. ATC templates may be used to have these additional codes link to the relevant databases: 

| ATC_supplemental ={{ATC|M02|AA15}}, {{ATC|S01|BC03}}

Adds the following linked codes:

For ATC - M02AA15, S01BC03

Veterinary drugs are placed in a slightly different classification system, ATCvet. The code may be specified as ATCvet by setting the parameter ATCvet to 'yes'. Do not include the leading 'Q' in ATC_prefix: 

| ATCvet            = yes
| ATC_prefix        = N05
| ATC_suffix        = AX90

Second identifier (like: CAS_number2)

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Chemical data

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Chemical formula

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Entering the chemical formula per element: 

| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= 
<!-- all 118 symbols -->
| charge=
| chemical_formula_ref =
| chemical_formula_comment =

E.g. 

| C=2 | H=6 | O=1 | charge=2-

gives

Formula Предлошка:Chembox Elements/molecular formula

This is called the empirical form, the most simple form. Entered this way, the elements are ordered in the Hill notation order: When C is present, CxHy in front and the others alphabetically Ar ... Zr. When a molecular formula or structural formula is known, that one should be entered in |chemical_formula= (consider using {{Chem}}).

You can provide the chemical formula as fixed 

| chemical_formula =
| chemical_formula_ref =
| chemical_formula_comment =

todo: example


Molar mass

When the chemical formula is entered as |C=2 |O=1 |H=6, the molar mass is calculated and presented. This value can be overwritten by using |molecular_weight= (sic). For more information, see {{Chem molar mass}}.

Other chemical data

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Additional chemical data fields are SMILES and standard МХП (optionally oncluding a comment and standard InChIKey). 

| SMILES            =
| StdInChI          =
| StdInChI_comment  =
| StdInChIKey       =

Physical data

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This is an entirely optional section, and for most drugs is not helpful to the wider readership. Only include if information of particular interest for the drug as to its chemical propersites (e.g. in its manufacture or as an important chemical in its own right, e.g. Aspirin). If any of the following optional parameters are defined then a new section header of 'Physical data' is shown. 

| density           = 
| melting_point     = 
| boiling_point     = 
| solubility        = 
| specific_rotation = 
| sec_combustion    =

The template will add the following to the numeric values provided:

  • Density - added 'g/cm3'
  • Melting or Boiling points - added '°C' along with calculated converted value in °F.
  • Solubility - added 'mg/mL (20 °C)'

Hence: 

| melting_point = 100

gives:

Melting point 100 °C (212 °F)

In addition, where the melting point occurs over a range of temperatures, use melting_high for the upper value.

Hence: 

| melting_point = 100
| melting_high  = 104

gives:

Melting point 100–104 °C (212–219 °F)

Comments can be added to the melting and boiling point entries using melting_notes and boiling_notes.

Hence: 

| boiling_point = 100
| boiling_notes = (sublimes)

gives:

Boiling point 100 °C (212 °F) (sublimes)

Section overview by |type= options

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A |type= uses some sectionsheader: 

| type=mab
| type=vaccine
| type=combo
| type=
Listed in Кат:Drugs by type

Предлошка:Infobox drug/doc/type-conditional sections

TemplateData

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Поврзано

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Преземено од „https://mk.wikipedia.org/w/index.php?title=Предлошка:Инфокутија_Лек&oldid=4930373“