Хероин: Разлика помеѓу преработките
| [непроверена преработка] | [проверена преработка] |
Избришана содржина Додадена содржина
сНема опис на уредувањето |
Нема опис на уредувањето |
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Ред 1:
{{Инфокутија Лек
| drug_name =
| type =
| IUPAC_name = (5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate
| image = Heroin - Heroine.svg
| alt =
| caption =
| image2 = Heroin-from-xtal-horizontal-3D-balls.png
<!--Clinical data-->| pronounce = Heroin: {{IPAc-en|ˈ|h|ɛ|r|o:|ɪ|n}}
| Drugs.com = {{drugs.com|parent|heroin}}
| MedlinePlus =
| licence_EU =
| licence_US =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X / N -->
| pregnancy_category =
| legal_AU = S9
| legal_CA = Schedule I
Ред 16 ⟶ 23:
| legal_US = Schedule I
| legal_UN = Narcotic Schedules I and IV
| legal_status =
| dependency_liability = Physical: Very high<br />Psychological: Very high
| addiction_liability = High<ref name=Drugs2014></ref>
| routes_of_administration =
| bioavailability = <35% (by mouth), 44–61% (inhaled)<ref name="pmid16433897">{{cite journal |vauthors=Rook EJ, van Ree JM, van den Brink W, Hillebrand MJ, Huitema AD, Hendriks VM, Beijnen JH | title = Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioid-dependent patients | journal = Basic Clin. Pharmacol. Toxicol. | volume = 98 | issue = 1 | pages = 86–96 | year = 2006 | pmid = 16433897 | doi = 10.1111/j.1742-7843.2006.pto_233.x }}</ref>
| protein_bound = 0% ([[morphine]] metabolite 35%)
| metabolism = [[
| onset = Within minutes<ref>{{cite book|last1=Riviello|first1=Ralph J.|title=Manual of forensic emergency medicine : a guide for clinicians|date=2010|publisher=Jones and Bartlett Publishers|location=Sudbury, Mass.|isbn=978-0-7637-4462-5|page=41|url=https://books.google.com/books?id=keng9ELAE2IC&pg=PA41|deadurl=no|archiveurl=https://web.archive.org/web/20170318224346/https://books.google.com/books?id=keng9ELAE2IC&pg=PA41|archivedate=18 March 2017|df=dmy-all}}</ref>
| elimination_half-life = 2–3 minutes<ref name=EMC>{{cite web|title=Diamorphine Hydrochloride Injection 30 mg – Summary of Product Characteristics|work=electronic Medicines Compendium|publisher=ViroPharma Limited|date=24 September 2013|accessdate=30 March 2014|url=http://www.medicines.org.uk/emc/medicine/28258/SPC/Diamorphine+Hydrochloride+Injection+30+mg/|deadurl=no|archiveurl=https://web.archive.org/web/20140330154716/http://www.medicines.org.uk/emc/medicine/28258/SPC/Diamorphine+Hydrochloride+Injection+30+mg/|archivedate=30 March 2014|df=dmy-all}}</ref>
| |||